Hi guys, I have a very dumb question, I have a Rancher installed on an Amazon EKS cluster, that is installed in the default VPC, then if I want to install a RKE cluster (managed by Rancher) in a different VPC than Rancher, should be made a VPC peering between VPC default and VPC of RKE?

You are correct. Also don't forget to add routes to the peering connection on both VPCs.

What kind of rules ?