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If it's a standard error number, then a quick web search for

errno 22

suggests it might be 'Invalid argument' (though nothing forces programmers to use standard error numbers).

ya, that is the error when I triggered pci passthrough through ui, I am expecting there are more configuration steps. but the docs didn’t tell much https://docs.harvesterhci.io/v1.1/advanced/pcidevices

Can't say I know anything about Harvester, I haven't used it myself. I just directly used KVM for my lab environment. You might try the #harvester channel? I don't know that one specifically, but I can say for some of the others you will definitely get more dedicated attention on the dedicated channel.